Can Dogs Get Hooked on Nicotine? The Surprising Truth


Nicotine addiction in dogs refers to compulsive tobacco use that leads to dependence on nicotine. It occurs when dogs are repeatedly exposed to nicotine, most often through secondhand smoke. Nicotine is an addictive stimulant found in tobacco products. When inhaled, it enters the bloodstream and stimulates dopamine release in the brain’s reward pathways. Over time, dogs can become hooked on this pleasurable dopamine hit and dependent on nicotine to function normally.

Understanding if and how dogs become addicted to nicotine is important for several reasons. First, nicotine toxicity can be fatal to dogs, so recognizing signs of addiction could save a dog’s life. Second, nicotine addiction may cause behavioral changes in dogs that affect training and relationships with owners. Finally, knowing the risks allows owners to prevent addiction by minimizing a dog’s exposure to secondhand smoke. This article will provide an in-depth look at how dogs become addicted, health consequences, diagnosis, treatment, and prevention.

How Dogs Absorb Nicotine

Dogs can absorb nicotine through ingestion, inhalation, or skin absorption. If a dog ingests nicotine gum, cigarettes, nicotine patches, e-cigarette liquid, or other tobacco products, the nicotine is rapidly absorbed through the mucous membranes in the mouth and digestive tract (Veterinary Partner – VIN). Nicotine can also be inhaled if a dog is in an enclosed space with tobacco smoke. The nicotine enters the lungs and crosses rapidly into the bloodstream, reaching peak levels within 10-20 minutes after inhalation (MSPCA Angell).

Dogs can also absorb nicotine through their skin if they come into contact with tobacco products or liquid nicotine. Nicotine is lipid-soluble and can be absorbed transdermally. The pads of a dog’s paws provide an optimal entry for the poison (WagWalking). Even brief skin exposure, such as stepping in spilled liquid nicotine, can deliver toxic amounts into a dog’s system.

Nicotine Metabolism in Dogs

a dog staring longingly at a pack of cigarettes on a table
Dogs metabolize nicotine differently than humans due to differences in their cytochrome P450 enzyme system. In humans, nicotine is primarily metabolized by the CYP2A6 enzyme. However, dogs lack this enzyme and instead utilize CYP2B11 to metabolize nicotine (source:

As a result, nicotine is metabolized at a slower rate in dogs compared to humans. The slower metabolism leads to nicotine persisting longer in a dog’s system. This longer persistence increases the chance of nicotine toxicity and long-term health effects in dogs.

Signs of Nicotine Toxicity

Nicotine toxicity can cause a wide range of concerning symptoms in dogs. Some of the most common signs of nicotine poisoning in dogs include:

  • Vomiting – Dogs may vomit repeatedly after ingesting nicotine. The vomit may contain pieces of the nicotine source (tobacco, e-cigarette juice, etc.)
  • Drooling – Excessive drooling is a common early symptom of nicotine toxicity.
  • Tremors – Dogs may shake or tremble uncontrollably due to nicotine’s effects on the nervous system.
  • Diarrhea – Nicotine irritation can cause diarrhea in dogs.
  • Elevated heart rate and blood pressure – Nicotine is a stimulant that can dangerously increase a dog’s heart rate and blood pressure.
  • Panting and restlessness – Dogs may pace anxiously and pant excessively as a result of nicotine poisoning.
  • Weakness and collapse – Serious nicotine toxicity can lead to muscle weakness, loss of coordination, collapse and even seizures.

According to PetMD, the signs of nicotine toxicity vary greatly depending on the amount and concentration of nicotine ingested (source). Mild poisoning may result in vomiting, while ingestion of concentrated liquid nicotine can rapidly cause collapse, seizures, and even death. If nicotine poisoning is suspected, immediate veterinary treatment is essential.

Long-Term Health Effects

Nicotine is a highly addictive stimulant, and long-term exposure can have detrimental health effects for dogs, similar to the chronic conditions seen in human smokers. Dogs are susceptible to lung disease and heart disease from chronic nicotine intake.

One of the most common long-term effects of nicotine exposure in dogs is bronchitis or other respiratory issues. Nicotine is an irritant to the airways and lungs. Over time, chronic inflammation of the bronchial tubes can develop into bronchitis or chronic obstructive pulmonary disease (COPD) 1. These conditions cause chronic coughing, wheezing, and difficulty breathing.

Nicotine also puts significant strain on the cardiovascular system. It causes blood vessels to constrict while increasing heart rate and blood pressure. With repeated exposure, this effect can lead to hypertension and atherosclerosis later in life 2. Cardiovascular disease like dilated cardiomyopathy is a serious potential outcome as well.

a dog receiving oxygen therapy from a veterinarian

The negative impacts of nicotine exposure accumulate over time. Quitting tobacco and preventing further access to nicotine sources is critical for dogs exhibiting any signs of addiction or toxicity.

Behavioral Effects

Nicotine can have significant behavioral effects in dogs. It acts as a stimulant by binding to nicotinic acetylcholine receptors in the brain, which causes the release of dopamine and other neurotransmitters. This provides a sense of reward and pleasure. [1]

In particular, nicotine can reinforce certain behaviors in dogs through operant conditioning. When a dog chews on tobacco products or consumes nicotine, the resulting stimulant effect acts as a positive reinforcer. This makes the dog more likely to repeat the behavior that led to the nicotine exposure. Over time, this can result in an addictive pattern of nicotine-seeking behavior. [2]

Common behavioral signs of nicotine exposure and reinforcement in dogs include increased excitement, hyperactivity, agitation, panting, drooling, digging, chewing, and consuming nicotine-containing products. Dogs may even learn to preferentially seek out cigarette butts. Without intervention, these behaviors can become compulsive in nature.

Diagnosing Nicotine Addiction

Nicotine toxicity in dogs is diagnosed based on clinical signs and known or suspected exposure to nicotine products (PetMD). Vets will perform a physical exam to check for symptoms like vomiting, diarrhea, increased heart rate and blood pressure, tremors, and seizures. Blood and urine tests may also be run to check for elevated levels of cotinine, a nicotine metabolite. These tests can confirm exposure and nicotine absorption even if the owner is unaware of it. Additionally, since nicotine is quickly metabolized and eliminated from the body, tests may be negative even when a dog has experienced nicotine toxicity.

Therefore, vets must rely heavily on clinical signs and owner reports to make a diagnosis of nicotine poisoning. Evidence of nicotine product packaging or witnessing the dog ingesting tobacco can aid diagnosis.

To assess for addiction, vets will evaluate if the clinical signs are recurrent and if the dog compulsively seeks out nicotine products. For example, a dog that repeatedly eats discarded cigarette butts could indicate an addictive disorder. Checking for withdrawal symptoms like anxiety, restlessness, and irritability when nicotine is removed can also help diagnose addiction (Le Foll, 2009). Overall, diagnosis involves piecing together clinical evidence, testing, and behavioral patterns indicative of pathological nicotine seeking behavior.


Dogs that have been exposed to nicotine and are showing signs of toxicity will need to be treated immediately by a veterinarian to prevent further harm. The main goals of treating nicotine poisoning in dogs are to remove any remaining nicotine in the dog’s system, provide supportive care, and help wean the dog off nicotine if addicted.

If the nicotine exposure occurred within the last 1-2 hours, the vet may induce vomiting or give activated charcoal to absorb any nicotine still in the stomach and prevent further absorption. They will also administer IV fluids to maintain blood pressure and support kidney function. Oxygen therapy may be used if the dog is having trouble breathing. Seizures, abnormal heart rhythms, tremors and other symptoms are managed with medications like valium, atropine or propranolol as needed.
a veterinarian administering an iv drip to a dog

For dogs addicted to nicotine through long-term secondhand exposure or ingestion of tobacco products, vets will develop a gradual tapering protocol to wean them off and manage withdrawal symptoms. This usually involves step-wise decreasing doses of nicotine replacement given orally or transdermally over the course of weeks to months. Anti-anxiety medications may be used to control agitation or restlessness during withdrawal. Close monitoring and supportive care are essential during the weaning process.

With prompt veterinary treatment, the prognosis for nicotine toxicity is often good if addressed quickly. However, chronic exposure can lead to long-lasting cardiovascular and neurologic effects. Preventing access to tobacco products is key to avoiding nicotine addiction and poisoning in dogs.



The best way to prevent nicotine poisoning in dogs is to keep all nicotine products out of their reach. Cigarettes, cigarette butts, nicotine gum, patches, vaping liquids, and any other item containing nicotine should be stored securely where dogs cannot access them. Dogs are very curious and will explore items left lying around, so nicotine products should never be left unattended (source).

If you or other household members do use nicotine products, be very diligent about disposing of them properly in trash cans with lids. Do not leave cigarette butts or discarded nicotine gum where your dog could eat them. Also be cautious when outside walking your dog, as they may pick up discarded cigarette butts while exploring or on walks (source).

Educate any visitors to your home not to leave nicotine products lying around. Make sure children know not to share nicotine gum or patches with pets. Seeing a loved one chewing nicotine gum may make your dog curious to try it too.

Dogs should never be allowed access to vaping devices or liquids, which can contain very high, potentially fatal doses of nicotine. Keep vaping tools and vials of liquid up and away securely. Even residues left on countertops could sicken a pet.

Being proactive is key to protecting your dog. Regularly inspect areas your dog has access to and discard any found nicotine products immediately. Keep trash cans covered and make sure any visitors know not to enable your dog’s access to items with nicotine.


a happy, healthy dog playing outdoors

In summary, dogs can experience nicotine toxicity and possibly addiction if exposed to tobacco products. Nicotine is readily absorbed through a dog’s mouth and nose, enters the bloodstream, and travels to the brain where it stimulates receptors that control the release of neurotransmitters like dopamine. This leads to feelings of reward and pleasure.

Signs of nicotine toxicity include drooling, vomiting, diarrhea, tremors, and seizures. With repeated exposure, dogs may show addiction-like behaviors as they crave more nicotine. Long-term health effects are still being studied but likely include an increased risk of certain cancers.

Preventing access to tobacco products, including cigarette butts, is crucial to protecting dogs from potential nicotine poisoning and addiction. If you suspect your dog has ingested nicotine, contact your veterinarian right away. Through increased awareness and vigilance, we can keep our canine companions safe.

The health and wellbeing of dogs should be the top priority for any pet owner. While more research is still needed, the available evidence clearly shows dogs can be harmed by nicotine exposure. Taking steps to prevent access and minimize risks is essential.

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